The Challenge
The sponsor had a long track record in global AMR surveillance, traditionally reliant on central labs to process and report microbiological data.
But this time, they wanted something more flexible. A faster, decentralised approach that could collect anonymised real-world data — both microbiological and clinical outcomes — directly from hospital sites.
Micron was tasked with enabling this shift: Build a solution that would accept structured data from local LIMS (Laboratory Information Management Systems) where possible, and manually where necessary — all while maintaining data integrity.
Micron’s Contribution
We activated 21 study sites across five countries:
🇮🇳 India, 🇲🇽 Mexico, 🇸🇦 Saudi Arabia, 🇪🇸 Spain, and 🇬🇧 the UK.
Depending on technical capability, each site submitted anonymised data:
Electronically via their LIMS
Or manually, supported by Micron’s onboarding and data teams
In total:
8,060 hospitalised patient records were submitted
7,444 (92%) were complete enough to include in the final analysis
All data was coded and processed by Micron’s internal data management team
To empower real-time use of the results, we built a secure, web-based portal where both study sites and the sponsor could view and analyse the AMR dataset via a custom database interface.
The Result
This pilot study successfully demonstrated the feasibility of using real-world data — including anonymised EHR and microbiological results — to track AMR and patient outcomes across international hospital sites.
Key takeaways:
The approach is scalable. This methodology can be applied to other therapy areas beyond AMR.
Flexibility is critical. Sites varied significantly in their data quality and technical infrastructure. A rigid, one-size-fits-all model wouldn’t have worked.
Data completeness matters. Compared to clinical trials, real-world EHRs may be relatively incomplete. But with the right tools and a site-aware strategy, valuable insights are still achievable.
"Team members are fully engaged and take responsibility for the studies as if they were their own."
Project Manager